| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7084
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7084
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate |
2004-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2007-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2007500697-A |
| titleOfInvention |
Method for reducing the toxicity of microbial pathogens and method for inhibiting microbial biofilm formation |
| abstract |
The present invention relates to the use of the cyclic dinucleotide c-di-GMP and its cyclic dinucleotide analogs in a method of reducing the toxicity of a microbial pathogen or in inhibiting or reducing colonization by a microbial pathogen. The methods of the invention can further inhibit microbial biofilm formation and treat bacterial infections. The microbial colonization or biofilm formation that is inhibited or reduced may be on the skin, or on the nasal or mucosal surface. Inhibited microbial colonization or biofilm formation is also the surface of medical devices, particularly those in close contact with the patient, and the surfaces of industrial and construction materials where microbial colonization and biofilm formation are of interest. It can be above. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016531842-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7311514-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10189873-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102551061-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020532585-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014109256-A1 |
| priorityDate |
2003-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |