http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007332049-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d24321bed2edef57b40e064ce34f0a6e |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-12 |
| filingDate | 2006-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbb1dd57a44e3bcbd8894492ef43c2a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa8ebb581d3899424f11f44cb2f62026 |
| publicationDate | 2007-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2007332049-A |
| titleOfInvention | Optically active benzyloxypyrrolidine derivative hydrochloride powder and process for producing the same |
| abstract | An object of the present invention is to provide an optically active benzyloxypyrrolidine derivative hydrochloride powder and a method for producing the same in a simple, high yield and safe manner. The following two steps, (First Step) In an organic solvent, the general formula (1) [Chemical 1] (In the formula, R represents an optical group represented by i) hydrogen, ii) an alkyl group having 1 to 4 carbon atoms, iii) an alkoxy group having 1 to 4 carbon atoms, and iv) a halogen group. A hydrochloric acid chlorination step in which hydrogen chloride is contacted with an active benzyloxypyrrolidine derivative, (Second step) A step of crystallizing the solution obtained in the first step, wherein the molar ratio of hydrogen chloride present in the system is determined with or without concentrating the solution and the optically active benzyloxypyrrolidine derivative. The isolation step for crystallization after adjusting to 0.9 to 1.2, A process for producing an optically active benzyloxypyrrolidine derivative hydrochloride powder comprising: [Selection figure] None |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007131597-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007119418-A |
| priorityDate | 2006-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.