abstract |
【Task】 In order to obtain particles that can be transported / injected without causing clogging or clogging in blood vessels, mainly in devices such as catheters, needles, and syringes that are mainly medical devices, or in blood vessels, hydrophilic polymer segments And a method for producing spherical and hydrophilic particles using a block copolymer comprising a hydrophobic polymer segment. [Solution] A solution comprising a block copolymer obtained by copolymerizing a hydrophilic polymer segment and a hydrophobic polymer segment, the weight ratio of the hydrophobic polymer segment to the hydrophilic polymer segment being 0.5 to 10 and an organic solvent ( (Oil phase) is added to an emulsification aid and an aqueous phase composed of a water-soluble organic solvent having a solubility parameter of 9 (cal / cm) 1/2 or more and 23 (cal / cm) 1/2 or less and water, and stirred. Spherical hydrophilic particles are produced by drying in liquid. [Selection figure] None |