| abstract |
PROBLEM TO BE SOLVED: To provide a circular DNA molecule useful for gene therapy or production of a recombinant protein and a method for producing the circular DNA molecule. A region comprising at least one useful nucleic acid sequence, wherein the region allowing replication of the nucleic acid sequence comprises an origin of replication derived from a plasmid or bacteriophage, and the origin of replication functions in a host cell. A circular DNA molecule useful for gene therapy, which requires the presence of at least one specific protein that is foreign to the host cell. [Selection] Figure 5 |