abstract |
The present invention provides a novel receptor homologue for a ligand designated OX2. Mammalian (eg, primate) OX2 receptors, nucleic acids encoding purified proteins and fragments thereof, antibodies (both polyclonal and monoclonal antibodies). A method of using the composition for both diagnostic and therapeutic utility. The present invention also provides a method of modulating the physiology or development of a cell or tissue culture cell, comprising contacting the cell with an agonist or antagonist of a mammalian OX2RH. [Selection figure] None |