| abstract |
The present invention provides a selective and potent neuronal nicotinic cholinergic compound useful for the control of synaptic transmission and a pharmaceutical composition containing the compound. Novel 3-pyridyloxymethyl heterocyclic ethers having the formula (I), their pharmaceutically effective pharmaceutical compositions. * Is a chiral center, n is an integer selected from 1, 2 or 3, X is oxygen or sulfur, R 1 is hydrogen, allyl, and C1-C6 alkyl, R 2 is hydrogen, or n When = 2, CH2OH, CH2F, CH2CN, etc. are indicated. A represents methylene or ethylene which may be substituted with an alkyl group. [Selection figure] None |