abstract |
Expressing large amounts of vacuolating toxins for use as diagnostic reagents or in vaccines. An isolated nucleic acid encoding a Helicobacter pylori vacuolating toxin, comprising a regulatory sequence for a vacA coding region of nucleic acid, H. pylori, consisting of nucleotides 101 to 3964 of a specific nucleotide sequence An isolated nucleic acid, a nucleic acid isolated from Helicobacter pylori, comprising another specific nucleotide sequence, an isolated nucleic acid that selectively hybridizes to the nucleic acid. [Selection figure] None |