| abstract |
【Task】 Organ transplant, lupus, multiple sclerosis, rheumatoid arthritis, psoriasis, type I diabetes and diabetic complications, cancer, asthma, atopic dermatitis, autoimmune thyroid disease, ulcerative colitis, Crohn's disease, Alzheimer's disease, It is an object to provide an immunosuppressant for leukemia and other autoimmune diseases. [Solution] The compound of formula (I) wherein R 1 , R 2 and R 3 are as described in the specification is an inhibitor of an enzyme protein tyrosine kinase such as Janus kinase (3), such as Organ transplant, lupus, multiple sclerosis, rheumatoid arthritis, psoriasis, type I diabetes and diabetic complications, cancer, asthma, atopic dermatitis, autoimmune thyroid disease, ulcerative colitis, Crohn's disease, Alzheimer's disease, It is a therapeutic agent useful as an immunosuppressant for leukemia and other autoimmune diseases. [Selection figure] None |