abstract |
Provided are novel compounds and peptides that bind to erythropoietin receptor. The amino acid sequence X 3 X 4 X 5 GPX 6 TWX 7 X 8 (SEQ ID NO :), which binds to and activates or acts as an EPO agonist, to the erythropoietin receptor (EPO-R), wherein , Each amino acid is indicated by a standard single letter abbreviation; X 3 is C; X 4 is R, H, L or W; X 5 is M, F or I; X 6 is 20 genetically encoded Peptides independently selected from any of the L-amino acids; X 7 is D, E, I, L or V; and X 8 is C; [Selection figure] None |