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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_364b93751e4e67fd7890cecd0e354943
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publicationDate 2007-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2007271266-A
titleOfInvention Highly sensitive single nucleotide polymorphism detection method by photocurrent
abstract The present invention provides a novel SNP analysis method using a photosensitizer and double-stranded DNA. Specifically, a novel SNP analysis method that enables efficient and high-precision detection of SNPs in target DNA while forming double strands by hybridization of probe DNA having SNP sites and target DNA ( That is, an SNP typing method) is provided. A probe DNA having a single nucleotide polymorphism site is hybridized with a target DNA to form a double-stranded DNA complex, and a photocurrent generated in the double-stranded DNA complex is measured, The present invention relates to a method for detecting a base at a single nucleotide polymorphism site of a target DNA. [Selection] Figure 5
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