| abstract |
[PROBLEMS] To provide a screening tool and method for therapeutic and / or prophylactic agents for allergic diseases and chronic inflammatory diseases. SOLUTION: Lysophosphatidylserine receptor protein, functional equivalent variant, or homologous protein, allergic disease, chronic inflammatory disease therapeutic / preventive agent screening tool, cells expressing the various proteins and the various Disclosed is a therapeutic / prophylactic agent screening tool for allergic diseases and chronic inflammatory diseases, which are transformed cells expressing a polypeptide transformed with an expression vector containing DNA encoding a protein. Also, a method for detecting a lysophosphatidylserine receptor ligand or antagonist or a lysophosphatidylserine receptor activity-attenuating agent using the screening tool, and a method for screening an agent for treating or preventing allergic diseases and chronic inflammatory diseases by the detection method Is disclosed. [Selection figure] None |