| abstract |
A composition containing varenicline or a pharmaceutically acceptable salt thereof, and control of the amount of impurities. In a varenicline-containing composition, one or more of its synthetic intermediates, some mononitro, monoamino, mixed aminonitro, diamino, or dinitro intermediates, has a concentration greater than 0 ppm and about A varenicline composition that is 500 ppm or less, about 100 ppm or less, or about 10 ppm or less. [Selection figure] None |