| abstract |
Disclosed is a novel compound that has S1P receptor agonist activity, exhibits an excellent effect as an immunosuppressive agent, and has few side effects and can be administered orally. SOLUTION: General formula (I) [Chemical 1] [Where: V is, -CH 2 -, - CH 2 -CH 2 -, - CH = CH -, - CH 2 -CH 2 -CH 2 -, - CH 2 -O-CH 2 - or -CH 2 -CH 2 - CH 2 —CH 2 — and the like; R 1 represents a hydrogen atom or a lower alkyl group; A represents —N (R 2 ) — or —O—; Z 1 and Z 2 each independently represent a hydrogen atom Q represents a —CH 2 —O—, —CH 2 —CH 2 —O—, —CH 2 —O—CH 2 — or the like; Y represents a halogen atom, a hydroxyl group, an alkyl group or an amino group; It represents a phenyl group which may have a substituent, or a 5- to 6-membered aromatic heterocyclic group which may have a substituent. ] Or a salt thereof, or a solvate thereof. [Selection figure] None |