http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007259835-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_29e239c86a5934daefc895b6f1cc10f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39a9f66181ba753d515b2c2ef8e707da |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate | 2006-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3145b37938214e3e128851e1e4fe3a4b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f72bf0ec4ab4c3b60e8fc09971108613 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d82507c70d6cffaae8fe5d786015de6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2489db18d4c9fdbbf1c74ebfdcda38a3 |
| publicationDate | 2007-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2007259835-A |
| titleOfInvention | Human Th1 / Th2 differentiation induction system and use thereof |
| abstract | [PROBLEMS] To provide a novel screening system capable of searching for compounds involved in the Ras / MAPK pathway or Ca 2+ / CN pathway, or compounds that modify human Th1 / Th2 differentiation induction under conditions in which those pathways move. . SOLUTION: Human naive CD4T cells are cultured under stimulation with an anti-CD3 antibody in a differentiation induction medium (Th1 differentiation induction conditions) containing IL-2, IL-12 and anti-IL-4 antibodies, or IL- 2. Culture under stimulation with anti-CD3 antibody in differentiation induction medium (Th2 differentiation induction condition) containing IL-4 and anti-IFNγ antibody, and further, anti-IL-4 antibody or anti-IFNγ antibody from the differentiation induction medium, respectively. A method for inducing Th1 and / or Th2 differentiation of human naïve CD4 T cells, further comprising culturing without stimulation with an anti-CD3 antibody under culture conditions excluding only the above. [Selection] Figure 6 |
| priorityDate | 2006-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 193.