abstract |
The present invention provides a dendrimer that is highly safe, can encapsulate DNA, and is useful as a gene transfer carrier. A dendrimer is composed of a hydrophilic unit or segment composed of polyoxyethylene units and a dendron having a fluorene unit. The dendron is a dendron of the g-th generation (g = 1 to 5) represented by the following formula, and can form micelles in water and encapsulate DNA. (Wherein X 1 represents a nitrogen atom, X 2 represents an imino group (—NH—), Y represents a spacer containing an amide bond, etc., and R 1 and R 2 are substituents) [Selection figure] None |