| abstract |
PROBLEM TO BE SOLVED: To provide a nucleoside derivative having an ester bond that is stable to alkaline hydrolysis conditions. SOLUTION: General formula (I): [Wherein, R 1 represents a trimethylsilyl group, R 2 and R 3 together form a benzene ring, R 4 represents a hydrogen atom, R 5 represents a hydrogen atom, etc. R 6 Represents a hydrogen atom or the like, and B represents a nucleobase residue optionally having a protecting group or a modifying group. ] The nucleoside derivative represented by this. [Selection figure] None |