| abstract |
Disclosed is a compound having an activity regulating action such as an agonistic or antagonistic action on farnesoid X receptor (FXR) and useful as an active ingredient of a medicament for the treatment of diseases associated with abnormal lipid metabolism. The following general formula (I): [Wherein, R 1 represents an alkyl group, an aryl group, or an aryloxy group; R 2 represents an aryl group; X represents an oxygen atom or a sulfur atom; and R 3 may have a substituent. A compound such as N, N-dibenzyl-3-((E) -2- {2-chloro-4- [3- (2,6-dichlorophenyl) -5-isopropylisoxa Sol-4-ylmethoxy] phenyl} vinyl) benzamide or the like. |