| abstract |
An improved composition for hyperlipidemia, atherosclerosis and other vascular conditions. The present invention provides compositions, therapeutic combinations and methods comprising the following, which may be useful for treating vascular conditions, diabetes, obesity and lowering plasma sterol levels: (a At least one peroxisome proliferator-activated receptor activator; and (b) at least one substituted azetidinone or substituted β-lactam sterol absorption inhibitor. Examples of vascular conditions that can be treated include hyperlipidemia (eg, atherosclerosis, hypercholesterolemia or sitosterolemia). [Selection figure] None |