| abstract |
[PROBLEMS] To provide a practical production method with high flexibility of lamellarin α-20 sulfate or an analog thereof. A compound (II) and a compound (III) are reacted to obtain a compound (IV), then reacted with a compound (V) to obtain a compound (VI), and then P 3 is selectively deprotected, hydrolyzed. Decomposition, decarboxylation, oxidative ring closure and oxidation give lamellarin compound (XI), followed by selective deprotection of P 2 , sulfate esterification, selective deprotection of P 1 and deprotection of P 4 to give compound (I ) (The symbols in the formula are as defined in the specification.) [Selection figure] None |