| abstract |
PROBLEM TO BE SOLVED: To provide an active compound of anti-hepatitis B virus (also referred to as HBV) and a therapeutic method thereof. Administration of a nucleotide prodrug of β-L-dideoxyadenosine, which is a stabilized nucleotide prodrug of nucleoside exhibiting anti-hepatitis B activity, and a second compound, AZT, etc. A method of treating a host, particularly a human, infected with HBV. Also, a pharmaceutical composition whose prodrug is mono, di, triphosphate or the like. [Selection figure] None |