| abstract |
[PROBLEMS] To develop a patch preparation that transdermally administers a drug that is liquid at or near room temperature into a living body, and in a patch preparation that uses a polyisobutylene-based adhesive as an adhesive, the bleeding of the drug can be suppressed. To provide a patch preparation having sufficient adhesive properties. A patch preparation 10 of the present invention has a pressure-sensitive adhesive layer 2 laminated on one side of a support 1. The pressure-sensitive adhesive layer 2 contains a branched monohydric alcohol having 12 to 28 carbon atoms, a drug that is liquid at or near room temperature (excluding the free base of bisoprolol), and a polyisobutylene-based pressure-sensitive adhesive. It is characterized by. Thereby, the compatibility with a polyisobutylene adhesive and a drug can be raised specifically. As a result, the compounding amount of the drug can be increased, the drug bleeding from the pressure-sensitive adhesive layer can be suppressed, and sufficient adhesive properties can be obtained in practical use. [Selection] Figure 1 |