| abstract |
PROBLEM TO BE SOLVED: There is an urgent need for a safe and useful therapeutic agent for chronic obstructive pulmonary disease. SOLUTION: General formula (I) [Chemical 1] (Wherein all symbols have the same meaning as in the specification), a salt thereof, a solvate thereof, a cyclodextrin inclusion compound or a prodrug thereof has a strong bronchodilator action. . Furthermore, the compound represented by the general formula (I) has an anti-inflammatory action. Therefore, the compound represented by the general formula (I) is effective for the treatment of respiratory diseases such as chronic obstructive pulmonary disease, adult respiratory distress syndrome emphysema, cystic fibrosis or chronic bronchitis. [Selection figure] None |