http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007181454-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c2d6cc21bc7bce139ac89fd102222f74 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2006-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1c8b7f88f6a5a4c8c9ed7387a57368d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adccc1d356a7c24f3c57301cbf7b30d5 |
| publicationDate | 2007-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2007181454-A |
| titleOfInvention | Highly sensitive detection method by microarray of DNA sequence encoding protein specifically selected by molecular display method |
| abstract | A highly sensitive detection method for molecules selected by a molecular display method is provided. A tiling array in which probes designed based on sequence information of mRNA encoding a candidate protein are immobilized, wherein the gap between probes is 25 bases or less on average, or the overlap between probes is average Prepare a tiling array designed to be 50% or less of the probe length, and select the DNA selected by the screening method using the matching molecule in which the protein and the nucleic acid encoding the protein are bound to each other. In the presence of nucleotides labeled with a ligand substance that does not inhibit hybridization, the RNA substance is subjected to RNA amplification, the amplified RNA is hybridized to a tiling array, and an adapter substance and a fluorescent substance that bind to the ligand substance Alternatively, label with a conjugate of a substance that activates chemiluminescence or chemiluminescence, and increase the intensity of fluorescence or luminescence. The nucleic acid encoding the protein that interacts with the target molecule is detected by measuring and detecting the interaction by analyzing the measurement result. [Selection] Figure 2 |
| priorityDate | 2005-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 172.