| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95eaed79dec59391549e8016815b3a8f |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-97 |
| filingDate |
2005-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99f28c1e11e61233238f660afec49634
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d00c989da9965c2daf7ce595f5b619d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fe10957ff5e28f75e0e0183ecf6a623
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e88cda1b46ae2b7e0383d7199381a40 |
| publicationDate |
2007-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2007176835-A |
| titleOfInvention |
Skin external preparation for improving skin barrier function and method for producing the same |
| abstract |
【Task】 The object was to provide means for improving the barrier function of the skin itself. [Solution] Skin barrier function can be easily evaluated by culturing epidermal keratinocytes on a support having micropores in a low-calcium liquid medium until confluent, and then culturing in a high-calcium liquid medium. It was found that an epidermis keratinocyte layer membrane can be obtained, and that the barrier function of the epidermis keratinocyte layer membrane was improved by applying an extract of the citrus genus Daidai pericarp (spruce) to this. By adding this extract to a skin external preparation, a skin external preparation that easily improves the barrier function of the skin itself was obtained. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010022327-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210144725-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7285504-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008007411-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008007412-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014091727-A |
| priorityDate |
2005-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |