| abstract |
To provide a DNA sequence (oligomer array) for detection and localization of methylated cytosine on genomic DNA. An array having the following PNA (peptide nucleic acid)-and / or DNA-oligomer sequences on a solid surface. Each sequence includes an oligomer composed of 6 to 20 bases, each including at least a sequence of general formula DDCGDD, general formula DDTGDD, general formula HHCGHH, or general formula HHCAHH. Here, H is any one of the bases of adenine (A), cytosine (C), or thymine (T), and D is any one of the bases of adenine (A), guanine (G), or thymine (T). The position of the oligomer on the surface is related to the sequence of the oligomer. [Selection figure] None |