http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007167054-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-483 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2006-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7e981da2ee1ce042d3c2f464ec8d30a |
publicationDate | 2007-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2007167054-A |
titleOfInvention | Visible light chromosome abnormality inducing ability test method and use thereof |
abstract | An object of the present invention is to provide a test method for the ability of a test substance to induce abnormalities in visible light chromosomes. A test substance is brought into contact with a cultured cell derived from a mammal (first step), and the cultured cell derived from a mammal contacted with the test substance in the first step is within 12 hours after the start of contact in the first step. Cultivated under visible light irradiation (second step), recovering the cultured cell derived from the mammal cultured in the second step, and preparing a chromosome specimen from the recovered cultured cell derived from the mammal (third Step), observe the chromosome specimen prepared in the third step, examine the presence or absence of the occurrence of chromosomal abnormality (fourth step), and determine the ability of the test substance to induce chromosomal aberrations in the visible light according to the result of the fourth step. The presence or absence or degree thereof is evaluated, and the test substance's ability to induce abnormalities in visible light chromosomes is tested (fifth step). The use of proflavine, acridine yellow, acridine orange, etc. as a positive control for the assay method is also provided. [Selection figure] None |
priorityDate | 2005-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.