| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc6553d095ca5f9b401601389b95f33e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4120caaf4997cf81d06cd4d834d404eb |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-583
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-58 |
| filingDate |
2005-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e4f179c182efc5b56486d0946fc90f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac73ccf815ed802e11117c6a32a570f0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac544550deef65136a08556a49427224
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e76cbc6f8eb47000daa66aa135a4304
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1dce9699b90067715f76e024ba510909 |
| publicationDate |
2007-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2007161639-A |
| titleOfInvention |
Use of snake venom-derived Lys49-phospholipase A2 as an antagonist for vascular endothelial growth factor receptor |
| abstract |
An exogenous inhibitor that has been found and searched for an exogenous inhibitor that can be used as an antagonist for vascular endothelial growth factor receptor type 2 (KDR) and that is also excellent in water solubility. Is used as a competitive inhibitor against KDR that effectively inhibits the cell proliferation-inducing action of vascular endothelial growth factor VEGF 165 through binding to KDR. Lys 49 -phospholipase A 2 from snake venom, or Ser 49 -phospholipase A 2 , in particular Lys 49 -phospholipase A 2 from the snake venom of Agkistrodon piscivorus piscivorus), inhibits binding of VEGF 165 to KDR Used as a competitive inhibitor. [Selection] Figure 2 |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103933073-A |
| priorityDate |
2005-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |