| abstract |
[PROBLEMS] Depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's disease, eating disorder, hypertension, gastrointestinal disease, drug dependence, cerebral infarction, cerebral ischemia, cerebral edema, head injury, inflammation, immune-related disease Of antagonists to CRF receptors that are effective as therapeutic or preventive agents for diseases considered to be associated with CRF such as alopecia, irritable bowel syndrome, sleep disorders, epilepsy, dermatitis, schizophrenia, and pain . A pyrrolopyrimidine or pyrrolopyridine derivative represented by the following formula [I] substituted with a cyclic amino group has a high affinity for a CRF receptor and is considered to involve CRF. It is effective against diseases. [Selection figure] None |