abstract |
A piperidinopyrimidine derivative (more specifically, minoxidil) composition is provided. As a pharmaceutically active ingredient, at least 5% by weight of piperidinopyrimidine derivative or a pharmaceutically acceptable salt thereof, piperidinopyrimidine derivative or a pharmaceutically acceptable salt thereof based on the total weight of the composition. A solvent composition comprising a solvent selected from an acid, water and / or lower alcohol in an amount that is substantially completely solubilized, and a co-solvent selected from one or more of the group consisting of an aromatic alcohol and a polyhydric alcohol A pharmaceutical composition for topical administration, wherein the co-solvent comprises propylene glycol, it is present in an amount of less than about 10% by weight. [Selection figure] None |