| abstract |
PROBLEM TO BE SOLVED: To provide a patch comprising a hydrophilic base having both basic physical properties of the base such as adhesion to skin and shape retention and efficient drug release. (A) One type of water-soluble polymer selected from 2-acrylamido-2-methylpropanesulfonic acid and / or a salt thereof, styrenesulfonic acid and / or a salt thereof, and N-vinylpyrrolidone. One or more polymers obtained by homopolymerizing a monomer, or obtained by copolymerizing one or more of the above monomers with other monomers copolymerizable And a water-soluble polymer mixture containing polyacrylic acid and / or a salt thereof, 20 to 60 mol% of the acid is neutralized, and the content of unreacted monomer in a fine powder is 0.5 mass%. A water-soluble polymer, (b) a polyhydric alcohol, (c) a polyvalent metal compound, (d) a surfactant and (e) a base for patch containing water, and a transdermal drug Alternatively, a patch obtained by applying an aqueous gel plaster containing a cosmetic ingredient on a support. [Selection figure] None |