| abstract |
[PROBLEMS] To find a novel PPAR activator. Furthermore, the present invention provides a skin external preparation composition or a whitening agent effective in preventing or improving rough skin, skin inflammation, and skin barrier function deterioration. A PPAR activator comprising one or more compounds selected from phenol derivatives, coumarins, and secoridoids as an active ingredient is provided. Moreover, the whitening agent and skin external composition which contain these compounds as an active ingredient are provided. It has an excellent PPARβ / δ activating action, and a skin external preparation composition containing this as an active ingredient is effective for the whitening effect, skin roughness and skin inflammation, and prevention / improvement of skin barrier function deterioration. [Selection figure] None |