| abstract |
Disclosed is a therapeutic agent for neurological diseases, mood disorders, pain and tobacco withdrawal symptoms associated with cerebral aging caused by agonists of α4β2 type central nicotinic receptors. In formula (I) (wherein n represents an integer of 1 to 6, R 1 and R 2 are a hydrogen atom, a (C 1 -C 6 ) alkyl group or an aryl- (C 1 -C). 6 ) represents an alkyl group, R 3 and R 4 represent a hydrogen atom or a (C 1 -C 6 ) alkyl group, R 5 and R 6 represent a hydrogen atom, or (C 1 -C 6 ) alkyl, halogen , Hydroxy, (C 1 -C 6 ) alkoxy, cyano, nitro, (C 2 -C 6 ) acyl, (C 1 -C 6 ) alkoxycarbonyl, (C 1 -C 6 ) trihaloalkyl, (C 1 -C 6 ) represents a trihaloalkoxy or an optionally substituted amino group. [Selection figure] None |