| abstract |
The present invention provides a novel cell line useful for elucidating the etiology of blastic NK cell lymphoma, and means useful for elucidating the immune mechanism via dendritic cells in humans using the cell line. An isolated human plasmacytoid dendritic cell line, a mature dendritic cell line obtained by treating the cell line with a differentiation-inducing agent, an experimental animal carrying the cell line, the cell line or Cellular components obtained from cells of experimental animals, antibodies obtained by inoculating animals other than humans with cell components obtained from the dendritic cell line, and the cell line are used, and are involved in immune responses Substance screening method. [Selection] Figure 1 |