abstract |
The present invention provides a novel nitrogen-containing heterocyclic compound or a salt thereof, an antioxidant containing the compound or a salt thereof, and a therapeutic agent containing the antioxidant. A compound represented by the formula (1) or a salt thereof, an antioxidant containing the compound or a salt thereof, and renal disease, cerebrovascular disease, cardiovascular disease, cerebral infarction containing the antioxidant Therapeutic agents, retinal oxidative disorder therapeutic agents, lipoxygenase inhibitors, 20-HETE synthase inhibitors. [Wherein R 1 represents a C 1-6 alkyl group, etc., l represents an integer of 0 to 10, m represents 1 or 2, Q represents oxozole, imidazole, indole and derivatives thereof, Y represents a carbon atom] , D represents an oxygen atom or the like, and E represents a chroman-2-yl group having at least NH 2 or the like as a substituent. ] [Selection figure] None |