http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007006713-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05c62f2cf821f016678afe25fbcd6ced http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e85961bb2dd7bc5dc990953233d799e |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2005-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09f891b495dfa637dd2f79b7df73f048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f6d1df2bd1602647544f9284d14b2d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da3d0720ee4fd9e7ecc7c1bf79f58323 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fc91dab1437d0d00ef88611e1ce9719 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4747c3788ce52c0a5fea4baf24dec87b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b2555b162fdda345ad3b64583da012b |
| publicationDate | 2007-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2007006713-A |
| titleOfInvention | Primer set for detecting polymorphism of drug metabolizing enzyme CYP1A2 gene, primer and probe, test agent for metabolic activity of the enzyme, and test method thereof |
| abstract | PROBLEM TO BE SOLVED: To detect a genetic polymorphism related to the metabolic ability of CYP1A2 before administering a drug metabolized by the drug metabolizing enzyme CYP1A2 including a bronchodilator theophylline as a pharmaceutical product, and to detect the amount of CYP1A2 in an amount appropriate for each patient. By administering a drug to be metabolized, a test drug capable of avoiding side effects due to the drug is provided. SOLUTION: A primer set, a primer and a probe capable of detecting a single nucleotide polymorphism at position 125, 1130 or 1367 on the CYP1A2 gene related to the metabolic ability of the drug-metabolizing enzyme CYP1A2, and the metabolic activity of the enzyme Administering an amount of a drug such as theophylline according to the CYP1A2 metabolic activity of each patient after determining abnormalities in drug metabolism based on the detected single nucleotide polymorphism as a test drug and its test method This makes it possible to avoid the side effects of drugs such as theophylline. [Selection] Figure 1 |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110923312-A |
| priorityDate | 2005-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 493.