| abstract |
The present invention provides a composition for use in allergen-specific immunotherapy that is safe and has a low risk of anaphylaxis. In addition to the entire amino acid sequence of allergens such as bee venom, camellia pollen, and dust mites, the composition also comprises consecutive overlapping peptide fragments. Administration of the composition does not show skin reactivity due to weak or inactive IgE irritation. It is possible to reduce the T cell response upon exposure in patients hypersensitive to protein allergens and modulate the patient's immune response. [Selection] Figure 1 |