| abstract |
The present invention relates to substituted pyrrolo [1,2-b] pyridazine compounds of formula I, stereoisomers thereof, pharmaceutically acceptable salts thereof, prodrugs thereof, or pharmaceutically acceptable salts of prodrugs thereof. The compound interacts with CRF 1 receptors including the human CRF 1 receptor. The present invention also uses the compounds of the present invention to treat CNS disorders and CNS diseases, particularly anxiety-related disorders such as anxiety and mood disorders such as major depression, by antagonizing the CRF receptor. Relates to a method of treating a disorder or condition that can affect or promote it. |