| abstract |
The present invention provides a method for the prevention or treatment of acute or chronic graft rejection, inflammation or autoimmune disease or malignant proliferative disease in a recipient of allogeneic or xenotransplantation of cells, tissues or organs, including the use of Vav inhibitors To do. Further provided are Vav inhibitors, uses involving Vav inhibitors, pharmaceutical compositions and therapeutic combinations, and screening methods thereof. |