http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006524496-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-102 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91215 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-566 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate | 2004-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2006-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2006524496-A |
| titleOfInvention | Methods and compositions targeting tyrosine kinases for diagnosis and treatment of osteoarthritis |
| abstract | The present invention indicates that members of the receptor tyrosine kinase subfamily including TYRO3, Axl, cMer and their ligands such as GAS6 are suitable targets for the development of new therapeutic agents to treat, prevent or ameliorate OA. Is disclosed. The present invention also relates to methods of treating and / or ameliorating OA and pharmaceutical compositions comprising modulators having an inhibitory effect on the expression or activity of members of this receptor tyrosine subfamily and related ligands. The present invention also relates to a method of identifying compounds having therapeutic utility for treating OA, including, for example, identifying compounds that can inhibit the activity and / or expression of these polypeptides. |
| priorityDate | 2003-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1377.