abstract |
The pyrazolo [1,5-a] pyrimidine derivatives represented by formula I and their pharmaceutically acceptable salts exhibit excellent kinase inhibitory activity. Therefore, a drug containing the compound as an active ingredient is used for treatment of protein kinase-mediated disorders that have been confirmed to be associated with kinases, such as inflammatory diseases, autoimmune diseases, destructive bone disorders, cancer and / or tumor growth. Expected to be useful as a drug or preventive. |