| abstract |
The present invention relates to solid oral dosage forms comprising one or more pharmacologically active ingredients solubilized or suspended in a pharmaceutically acceptable solvent or liquid phase and encapsulated in seamless release controlled microcapsules. . Accordingly, pharmaceutically acceptable solvents or liquid phases include those of water phase, organic solvents, glycols, oils, and mono-, di-, and tri-glycerides of short, medium and long chain fatty acids. The range can be up to a derivative. Microcapsules have a diameter of less than 1 mm to 8 mm and their drug loading is up to 90%. Further, the microcapsules can be coated to release the pharmacologically active ingredient at a specific site and at a predetermined rate. |