| abstract |
The present invention relates to novel pyridazinone derivatives of formula (I) (wherein R 1 to R 4 , R 7 , R 8 and X 1 are as defined in the summary) as well as pharmaceutically acceptable salts thereof and Solvates, methods for inhibiting or modulating human immunodeficiency virus (HIV) reverse transcriptase with compounds of formula (I), compounds of formula (I) mixed with at least one solvent, carrier or excipient And a method for producing a compound of formula (I). The compounds are useful for treating diseases involving HIV and genetically related viruses. |