| abstract |
Disclosed are peptides that selectively kill malignant or transformed cells, and adenoviral vectors (AdV) containing a transgene encoding these peptides. A promoter sequence operably linked to a nucleotide sequence encoding a peptide, wherein the peptide consists of at least about 6 consecutive amino acids of the amino acid sequence PPLSQETFSDLWKLL (SEQ ID NO: 1) or an analog or derivative thereof. An incompetent adenovirus (AdV) vector. |