| abstract |
The present application provides a novel human gene MICAL2-PV whose expression is markedly elevated in prostate cancer. In addition, the application provides a polypeptide encoded by the gene, as well as a polypeptide encoded by PCOTH that has also been found to be upregulated in prostate cancer. These genes and polypeptides encoded by these genes are used, for example, in the diagnosis of prostate cancer, as target molecules for developing drugs against the disease, and to attenuate prostate cancer cell growth Can do. |