abstract |
The present invention relates to a method of treating a tumor or proliferative disorder associated with angiogenesis, the method comprising administering γ-secretase and β-secretase that inhibit secretase involved in amyloid precursor protein processing. Include. In particular, the method comprises at least one inhibiting carrier and secretase APP processing to treat a tumor or proliferative disorder or to inhibit angiogenesis associated with a tumor, proliferative disorder or inflammatory disorder. By administering a therapeutically effective amount of a composition in unit dosage form comprising a γ-secretase inhibitor or a β-secretase inhibitor to an animal or human in need of such treatment or angiogenesis inhibition, such as Provided in animals or humans in need of treatment or angiogenesis inhibition. |