| abstract |
This invention provides a compound of formula I or a pharmaceutically acceptable salt thereof, wherein G 1 , Q, D, and G 2 are as defined for formula I. The compound of formula I or a pharmaceutically acceptable salt thereof is an inhibitor of MMP-13. This compound is useful for treating diseases mediated by the MMP-13 enzyme, including those listed herein such as breast cancer, cartilage damage, rheumatoid arthritis, and osteoarthritis. [Chemical 1] |