http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006517032-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate | 2004-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2006-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2006517032-A |
| titleOfInvention | Methods for assessing the effectiveness of certain cancer treatments |
| abstract | A method for assessing the effectiveness of a therapeutic agent that acts to stimulate apoptosis in a mammalian body is obtained from a body tissue or fluid in which tumor cells are present from a mammal that is treated with the therapeutic agent that acts to stimulate apoptosis. Where the tissue or fluid may contain a 17 kDa fragment of caspase 3, which is generated by specific cleavage of caspase 3 in vivo; Assaying the sample to determine the abundance of a 17 kDa fragment; administering the therapeutic agent to the mammal; obtaining a second sample of the body tissue or fluid from the mammal; and the cleaved caspase Assaying the second sample to determine the abundance of three 17 kDa fragments, and measuring with the first sample An increase in the amount of the 17 kDa fragment measured in the second sample relative to the measured amount indicates the efficacy of the apoptotic stimulus and the therapeutic agent. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022075439-A1 |
| priorityDate | 2003-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 145.