| abstract |
The present invention relates to substituted phenyl- (2- [1,3,4] thiadiazol-2-ylphenyl) -amine compounds and substituted phenyl (2- [2- [1,3,4] thiadiazol-2-ylphenyl) amines that act as inhibitors of the MAPK / ERK kinase (“MEK”) enzyme. 1,3,4] oxadiazol-2-ylphenyl) phenyl-amine compounds and pharmaceutical compositions are provided, and also in immune preparation and in the treatment and alleviation of inflammation and proliferative diseases such as cancer and restenosis These usages are provided. |