http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006516189-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-3092 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
filingDate | 2003-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2006-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2006516189-A |
titleOfInvention | CA125 gene and its use for diagnosis and therapy |
abstract | The CA125 gene was cloned and multiple repeats and the carboxy terminus were identified. The CA125 molecule contains three major domains: an extracellular amino-terminal region (domain 1); a large multi-repeat region (domain 2); and a carboxy-terminal region containing a transmembrane region with a short cytoplasmic region (domain 3). . The amino terminal region is assembled by joining five genomic exons, ie four very short amino terminal sequences and one unusually large exon. This region is characterized by O-glycosylation capacity and the resulting richness of serine and threonine residues. In addition, there is an amino terminal extension that includes four genomic exons. It was revealed that the amino terminal amino acid composition was identical to the amino terminal amino acid composition. In this molecular structure, a repeat region containing 156 amino acid repeat units containing the epitope binding site is dominant. More than 60 repeat units were revealed, sequenced and placed adjacent in the CA125 domain structure. More specifically, the present invention relates to CA125 cDNA that can be introduced into animal or human cells and transcribed or expressed. |
priorityDate | 2002-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.