| abstract |
Indazole compounds that modulate and / or inhibit the activity of certain protein kinases with eye diseases are described. These compounds and pharmaceutical compositions containing them are capable of mediating tyrosine kinase signaling, thereby modulating and / or inhibiting unwanted cell proliferation. The present invention also provides therapeutic or prophylactic use of pharmaceutical compositions containing such compounds and administration of effective amounts of such compounds to prevent diabetic retinopathy, neovascular glaucoma, rheumatoid arthritis, and psoriasis. To methods of treating ocular diseases and cancer and other disease states associated with unwanted angiogenesis and / or cell proliferation. |